600Mb/s Authentication IP Core for AXI-4 Streams Optimized for Area
MD5 Stream Authentication IP Cores converts streams of data into streams of MD5 hash keys. This IP is fully compatible with compatible with RFC 1321 – The MD5 Message-Digest Algorithm  when data sizes are multiples of 64 bytes. The core outputs the 128-bit value (i.e. the hash key) when the End of Packet (EOP) Stream is received.
This core can be used in various applications that require authentication. For example, if two data streams generate the same hash key, then both data streams are almost certainly identical. While it is technically possible have a collision with MD5, it probability is extremely small. This is a widely researched topic with numerous technical papers on the strength of MD5.